Adenovirus protein IX sequesters host-cell promyelocytic leukaemia protein and contributes to efficient viral proliferation

The product of adenovirus type 5 (Ad5) gene IX, protein IX (pIX), is a multifunctional protein that stabilizes the viral capsid and has transcriptional activity. We show that pIX also contributes to the Ad5-induced reorganization of the host-cell nuclear ultrastructure: pIX induces the formation of...

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Bibliographic Details
Main Authors: Rosa-Calatrava, Manuel, Puvion-Dutilleul, Francine, Lutz, Pierre, Dreyer, Dominique, De Thé, Hugues, Chatton, Bruno, Kedinger, Claude
Format: Artigo
Language:Inglês
Published: 2003
Subjects:
Scientific Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1326401/
https://ncbi.nlm.nih.gov/pubmed/14528266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.embor943
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