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Role of the promyelocytic leukaemia protein in cell death regulation

The promyelocytic leukaemia gene PML was originally identified at the t(15;17) translocation of acute promyelocytic leukaemia, which generates the oncogene PML-retinoic acid receptor α. PML epitomises a subnuclear structure called PML nuclear body. Current models propose that PML through its scaffol...

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Detalhes bibliográficos
Main Authors: Salomoni, P, Dvorkina, M, Michod, D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3270264/
https://ncbi.nlm.nih.gov/pubmed/22237204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2011.122
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