Efficient transgenesis in farm animals by lentiviral vectors

Microinjection of DNA is now the most widespread method for generating transgenic animals, but transgenesis rates achieved this way in higher mammals are extremely low. To address this longstanding problem, we used lentiviral vectors carrying a ubiquitously active promoter (phosphoglycerate kinase,...

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Detalhes bibliográficos
Main Authors: Hofmann, Andreas, Kessler, Barbara, Ewerling, Sonja, Weppert, Myriam, Vogg, Barbara, Ludwig, Harald, Stojkovic, Miodrag, Boelhauve, Marc, Brem, Gottfried, Wolf, Eckhard, Pfeifer, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Scientific Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1326377/
https://ncbi.nlm.nih.gov/pubmed/14566324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400007
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