The 18-wheeler mutation reveals complex antibacterial gene regulation in Drosophila host defense.

Mammals and insects employ similar Rel/NF-kappaB signaling cascades in their humoral immune responses. The mammalian interleukin-1 type I receptor (IL-1R) is one way of activating this cascade. The Drosophila Toll protein, whose cytoplasmic domain shows striking similarity to that of the IL-1R, acts...

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Bibliografiske detaljer
Main Authors: Williams, M J, Rodriguez, A, Kimbrell, D A, Eldon, E D
Format: Artigo
Sprog:Inglês
Udgivet: 1997
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1326296/
https://ncbi.nlm.nih.gov/pubmed/9321392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.20.6120
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