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The 18-wheeler mutation reveals complex antibacterial gene regulation in Drosophila host defense.
Mammals and insects employ similar Rel/NF-kappaB signaling cascades in their humoral immune responses. The mammalian interleukin-1 type I receptor (IL-1R) is one way of activating this cascade. The Drosophila Toll protein, whose cytoplasmic domain shows striking similarity to that of the IL-1R, acts...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
1997
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1326296/ https://ncbi.nlm.nih.gov/pubmed/9321392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.20.6120 |
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