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Giα and Gβ subunits both define selectivity of G protein activation by α2-adrenergic receptors

Previous studies of the specificity of receptor interactions with G protein subunits in living cells have relied on measurements of second messengers or other downstream responses. We have examined the selectivity of interactions between α2-adrenergic receptors (α2R) and various combinations of Giα...

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Autors principals: Gibson, Scott K., Gilman, Alfred G.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1325004/
https://ncbi.nlm.nih.gov/pubmed/16371464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509763102
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