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Involvement of both G protein αs and βγ subunits in β-adrenergic stimulation of vascular L-type Ca(2+) channels

1. Previous data have shown that activation of β(3)-adrenoceptors stimulates vascular L-type Ca(2+) channels through a Gαs-induced stimulation of the cyclic AMP/PKA pathway. The present study investigated whether β-adrenergic stimulation also uses the Gβγ/PI3K/PKC pathway to modulate L-type Ca(2+) c...

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Detalhes bibliográficos
Main Authors: Viard, Patricia, Macrez, Nathalie, Mironneau, Chantal, Mironneau, Jean
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572606/
https://ncbi.nlm.nih.gov/pubmed/11159719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703864
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