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CYP27B1 null mice with LacZreporter gene display no 25-hydroxyvitamin D(3)-1α-hydroxylase promoter activity in the skin
The hormonally active form of vitamin D(3),1α,25-dihydroxyvitamin D(3) [1,25(OH)(2)D(3)], is synthesized in the kidney through a tightly regulated reaction catalyzed by 25-hydroxyvitamin D(3)-1α-hydroxylase (1α-hydroxylase), the product of the CYP27B1 gene. Through gene targeting in embryonic stem c...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1325002/ https://ncbi.nlm.nih.gov/pubmed/16371465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509734103 |
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