Toll-like receptor (TLR) polymorphisms in African children: Common TLR-4 variants predispose to severe malaria

Genetic host factors play a substantial role in susceptibility to and severity of malaria, which continues to cause at least one million deaths per year. Recently, members of the toll-like receptor (TLR) family have been shown to be involved in recognition of the etiologic organism Plasmodium falcip...

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Detalhes bibliográficos
Main Authors: Mockenhaupt, Frank P., Cramer, Jakob P., Hamann, Lutz, Stegemann, Miriam S., Eckert, Jana, Oh, Na-Ri, Otchwemah, Rowland N., Dietz, Ekkehart, Ehrhardt, Stephan, Schröder, Nicolas W. J., Bienzle, Ulrich, Schumann, Ralf R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1324982/
https://ncbi.nlm.nih.gov/pubmed/16371473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506803102
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