Concurrence of Plasmodium falciparum dhfr and crt mutations in northern Ghana

BACKGROUND: Both chloroquine (CQ) and sulfadoxine-pyrimethamine (SP) are failing drugs in much of sub-Saharan Africa. Previous findings suggest an association between resistance to CQ and to SP in vivo, in vitro, and on the molecular level. METHODS: In 126 Ghanaian children with uncomplicated malari...

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Detalhes bibliográficos
Main Authors: Mockenhaupt, Frank P, Bousema, J Teun, Eggelte, Teunis A, Ehrhardt, Stephan, Otchwemah, Rowland N, Sauerwein, Robert W, Bienzle, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1261531/
https://ncbi.nlm.nih.gov/pubmed/16164748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-4-42
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