Control of SRF binding to CArG box chromatin regulates smooth muscle gene expression in vivo

Precise control of SMC transcription plays a major role in vascular development and pathophysiology. Serum response factor (SRF) controls SMC gene transcription via binding to CArG box DNA sequences found within genes that exhibit SMC-restricted expression. However, the mechanisms that regulate SRF...

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Hlavní autoři: McDonald, Oliver G., Wamhoff, Brian R., Hoofnagle, Mark H., Owens, Gary K.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2006
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1323266/
https://ncbi.nlm.nih.gov/pubmed/16395403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI26505
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