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Structural changes involved in protein binding correlate with intrinsic motions of proteins in the unbound state
Protein–protein binding usually involves structural changes that may extend beyond the rearrangements on a local scale, and cannot be explained by a classical lock-and-key mechanism. Several models have been advanced to explain the flexible binding of proteins such as the induced fit mechanism where...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2005
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1323175/ https://ncbi.nlm.nih.gov/pubmed/16354836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0507603102 |
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