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Structural changes involved in protein binding correlate with intrinsic motions of proteins in the unbound state

Protein–protein binding usually involves structural changes that may extend beyond the rearrangements on a local scale, and cannot be explained by a classical lock-and-key mechanism. Several models have been advanced to explain the flexible binding of proteins such as the induced fit mechanism where...

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Detalhes bibliográficos
Main Authors: Tobi, Dror, Bahar, Ivet
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1323175/
https://ncbi.nlm.nih.gov/pubmed/16354836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0507603102
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