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Disruption of Cryptochrome partially restores circadian rhythmicity to the arrhythmic period mutant of Drosophila

The Drosophila melanogaster circadian clock is generated by interlocked feedback loops, and null mutations in core genes such as period and timeless generate behavioral arrhythmicity in constant darkness. In light-dark cycles, the elevation in locomotor activity that usually anticipates the light on...

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Detalhes bibliográficos
Main Authors: Collins, Ben H., Dissel, Stephane, Gaten, Edward, Rosato, Ezio, Kyriacou, Charalambos P.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1323156/
https://ncbi.nlm.nih.gov/pubmed/16361445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505392102
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