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Synthesis and hybridization studies of oligonucleotides containing 1-(2-deoxy-2-α-C-hydroxymethyl-β-d-ribofuranosyl)thymine (2′-α-hm-dT)

We report the first investigation of oligoribonucleotides containing a few 1-(2-deoxy-2-α-C-hydroxymethyl-β-d-ribofuranosyl)thymine units (or 2′-hm-dT, abbreviated in this work as ‘H’). Both the 2′-CH(2)O-phosphoramidite and 3′-O-phosphoramidite derivatives of H were synthesized and incorporated int...

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Hlavní autoři: Peng, Chang Geng, Damha, Masad J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1322267/
https://ncbi.nlm.nih.gov/pubmed/16377780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki1003
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