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Solution structure of a multifunctional DNA- and protein-binding motif of human Werner syndrome protein
Werner syndrome (WS) is an autosomal recessive disease that results in premature aging. Mutations in the WS gene (WRN) result in a loss of expression of the WRN protein and predispose WS patients to accelerated aging. As a helicase and a nuclease, WRN is unique among the five human RecQ helicase fam...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2005
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1317980/ https://ncbi.nlm.nih.gov/pubmed/16339893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509380102 |
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