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Crystal structure of receptor-binding C-terminal repeats from Clostridium difficile toxin A
Clostridium difficile is a major nosocomial pathogen that produces two large protein toxins [toxin A (TcdA) and toxin B (TcdB)] capable of disrupting intestinal epithelial cells. Both belong to the family of large clostridial cytotoxins, which are characterized by the presence of a repetitive C-term...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2005
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1317924/ https://ncbi.nlm.nih.gov/pubmed/16344467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506391102 |
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