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Amplified Expression of Fructose 1,6-Bisphosphatase in Corynebacterium glutamicum Increases In Vivo Flux through the Pentose Phosphate Pathway and Lysine Production on Different Carbon Sources

The overexpression of fructose 1,6-bisphosphatase (FBPase) in Corynebacterium glutamicum leads to significant improvement of lysine production on different sugars. Amplified expression of FBPase via the promoter of the gene encoding elongation factor TU (EFTU) increased the lysine yield in the feedb...

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Autori principali: Becker, Judith, Klopprogge, Corinna, Zelder, Oskar, Heinzle, Elmar, Wittmann, Christoph
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1317465/
https://ncbi.nlm.nih.gov/pubmed/16332851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.71.12.8587-8596.2005
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