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Amplified Expression of Fructose 1,6-Bisphosphatase in Corynebacterium glutamicum Increases In Vivo Flux through the Pentose Phosphate Pathway and Lysine Production on Different Carbon Sources

The overexpression of fructose 1,6-bisphosphatase (FBPase) in Corynebacterium glutamicum leads to significant improvement of lysine production on different sugars. Amplified expression of FBPase via the promoter of the gene encoding elongation factor TU (EFTU) increased the lysine yield in the feedb...

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Autors principals: Becker, Judith, Klopprogge, Corinna, Zelder, Oskar, Heinzle, Elmar, Wittmann, Christoph
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1317465/
https://ncbi.nlm.nih.gov/pubmed/16332851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.71.12.8587-8596.2005
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