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Improvement of Catalytic Properties of Escherichia coli Penicillin G Acylase Immobilized on Glyoxyl Agarose by Addition of a Six-Amino-Acid Tag

A tag of three lysines alternating with three glycines was added to the C-terminal end of the β chain of penicillin G acylase (PGA). This modification improved the immobilization efficiency of PGA on glyoxyl agarose and the catalytic properties of the PGA derivative, although it impaired the posttra...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Scaramozzino, Francesca, Estruch, Ilona, Rossolillo, Paola, Terreni, Marco, Albertini, Alessandra M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1317310/
https://ncbi.nlm.nih.gov/pubmed/16332894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.71.12.8937-8940.2005
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