periostin Null Mice Exhibit Dwarfism, Incisor Enamel Defects, and an Early-Onset Periodontal Disease-Like Phenotype

Periostin was originally identified as an osteoblast-specific factor and is highly expressed in the embryonic periosteum, cardiac valves, placenta, and periodontal ligament as well as in many adult cancerous tissues. To investigate its role during development, we generated mice that lack the periost...

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Bibliographic Details
Main Authors: Rios, Hector, Koushik, Shrinagesh V., Wang, Haiyan, Wang, Jian, Zhou, Hong-Ming, Lindsley, Andrew, Rogers, Rhonda, Chen, Zhi, Maeda, Manabu, Kruzynska-Frejtag, Agnieszka, Feng, Jian Q., Conway, Simon J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1316984/
https://ncbi.nlm.nih.gov/pubmed/16314533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.24.11131-11144.2005
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