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The Carboxy-Terminal Neh3 Domain of Nrf2 Is Required for Transcriptional Activation

Nrf2 is a transcription factor critical for the maintenance of cellular redox homeostasis. We have previously found that Nrf2 is a labile protein, and its activation in cells under stress involves mechanisms leading to its stabilization. As a modular protein, Nrf2 possesses distinct transactivation...

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Détails bibliographiques
Auteurs principaux: Nioi, Paul, Nguyen, Truyen, Sherratt, Philip J., Pickett, Cecil B.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1316965/
https://ncbi.nlm.nih.gov/pubmed/16314513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.24.10895-10906.2005
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