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Analysis of hepatic gene transcription in mice expressing insulin-insensitive GSK3

GSK3 (glycogen synthase kinase-3) regulation is proposed to play a key role in the hormonal control of many cellular processes. Inhibition of GSK3 in animal models of diabetes leads to normalization of blood glucose levels, while high GSK3 activity has been reported in Type II diabetes. Insulin inhi...

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Detalhes bibliográficos
Main Authors: Lipina, Christopher, Huang, Xu, Finlay, David, J McManus, Edward, R. Alessi, Dario, Sutherland, Calum
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1316304/
https://ncbi.nlm.nih.gov/pubmed/16176184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051046
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