Specific role for p85/p110β in GTP-binding-protein-mediated activation of Akt

We prepared CHO (Chinese hamster ovary) cells expressing both IR (insulin receptor) and A(1)R (A(1) adenosine receptor). Treatment of the cells with insulin or PIA [N(6)-(2-phenylisopropyl)adenosine], a specific A(1)R agonist increased Akt activity in the cells in a PI3K- (phosphoinositide 3-kinase)...

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Detalhes bibliográficos
Main Authors: Kubo, Hiroshi, Hazeki, Kaoru, Takasuga, Shunsuke, Hazeki, Osamu
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2005
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1316301/
https://ncbi.nlm.nih.gov/pubmed/16091017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050671
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