Th-Cytotoxic T-Lymphocyte Chimeric Epitopes Extended by N(ɛ)-Palmitoyl Lysines Induce Herpes Simplex Virus Type 1-Specific Effector CD8(+) Tc(1) Responses and Protect against Ocular Infection

Molecularly defined vaccine formulations capable of inducing antiviral CD8(+) T-cell-specific immunity in a manner compatible with human delivery are limited. Few molecules achieve this target without the support of an appropriate immunological adjuvant. In this study, we investigate the potential o...

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Detalhes bibliográficos
Main Authors: Zhang, Xiuli, Issagholian, Annie, Berg, Eric A., Fishman, Jordan B., Nesburn, Anthony B., BenMohamed, Lbachir
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1316035/
https://ncbi.nlm.nih.gov/pubmed/16306600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.24.15289-15301.2005
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