SOCS1 and SOCS3 Are Targeted by Hepatitis C Virus Core/gC1qR Ligation To Inhibit T-Cell Function

T cells play an important role in the control of hepatitis C virus (HCV) infection. We have previously demonstrated that the HCV core inhibits T-cell responses through interaction with gC1qR. We show here that core proteins from chronic and resolved HCV patients differ in sequence, gC1qR-binding abi...

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Detalhes bibliográficos
Main Authors: Yao, Zhi Qiang, Waggoner, Stephen N., Cruise, Michael W., Hall, Caroline, Xie, Xuefang, Oldach, David W., Hahn, Young S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1315996/
https://ncbi.nlm.nih.gov/pubmed/16306613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.24.15417-15429.2005
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