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Signal Peptide Cleavage and Internal Targeting Signals Direct the Hepatitis C Virus p7 Protein to Distinct Intracellular Membranes

The hepatitis C virus (HCV) p7 protein forms an amantadine-sensitive ion channel required for viral replication in chimpanzees, though its precise role in the life cycle of HCV is unknown. In an attempt to gain some insights into p7 function, we examined the intracellular localization of p7 using ep...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Griffin, Stephen, Clarke, Dean, McCormick, Christopher, Rowlands, David, Harris, Mark
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1315988/
https://ncbi.nlm.nih.gov/pubmed/16306623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.24.15525-15536.2005
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