Signal Peptide Cleavage and Internal Targeting Signals Direct the Hepatitis C Virus p7 Protein to Distinct Intracellular Membranes

The hepatitis C virus (HCV) p7 protein forms an amantadine-sensitive ion channel required for viral replication in chimpanzees, though its precise role in the life cycle of HCV is unknown. In an attempt to gain some insights into p7 function, we examined the intracellular localization of p7 using ep...

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Autores principales: Griffin, Stephen, Clarke, Dean, McCormick, Christopher, Rowlands, David, Harris, Mark
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2005
Materias:
Virus-Cell Interactions
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1315988/
https://ncbi.nlm.nih.gov/pubmed/16306623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.24.15525-15536.2005
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