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The 37 kDa/67 kDa laminin receptor is required for PrP(Sc) propagation in scrapie-infected neuronal cells

The accumulation of PrP(Sc) in scrapie-infected neuronal cells has been prevented by three approaches: (i) transfection of ScMNB cells with an antisense laminin receptor precursor (LRP) RNA-expression plasmid, (ii) transfection of ScN2a cells and ScGT1 cells with small interfering RNAs (siRNAs) spec...

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Detalhes bibliográficos
Main Authors: Leucht, Christoph, Simoneau, Steve, Rey, Clémence, Vana, Karen, Rieger, Roman, Lasmézas, Corinne Ida, Weiss, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1315896/
https://ncbi.nlm.nih.gov/pubmed/12634848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.embor768
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