Parkin binds the Rpn10 subunit of 26S proteasomes through its ubiquitin-like domain

Parkin, a product of the causative gene of autosomal-recessive juvenile parkinsonism (AR-JP), is a RING-type E3 ubiquitin ligase and has an amino-terminal ubiquitin-like (Ubl) domain. Although a single mutation that causes an Arg to Pro substitution at position 42 of the Ubl domain (the Arg 42 mutat...

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Detalhes bibliográficos
Main Authors: Sakata, Eri, Yamaguchi, Yoshiki, Kurimoto, Eiji, Kikuchi, Jun, Yokoyama, Shigeyuki, Yamada, Shingo, Kawahara, Hiroyuki, Yokosawa, Hideyoshi, Hattori, Nobutaka, Mizuno, Yoshikuni, Tanaka, Keiji, Kato, Koichi
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Scientific Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1315892/
https://ncbi.nlm.nih.gov/pubmed/12634850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.embor764
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