Characterization of Toll-like receptors in primary lung epithelial cells: strong impact of the TLR3 ligand poly(I:C) on the regulation of Toll-like receptors, adaptor proteins and inflammatory response

BACKGROUND: Bacterial and viral exacerbations play a crucial role in a variety of lung diseases including COPD or asthma. Since the lung epithelium is a major source of various inflammatory mediators that affect the immune response, we analyzed the inflammatory reaction of primary lung epithelial ce...

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Hlavní autoři: Ritter, Mirko, Mennerich, Detlev, Weith, Andreas, Seither, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2005
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1315317/
https://ncbi.nlm.nih.gov/pubmed/16316467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-9255-2-16
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