A Transgenic Rabbit Model for Human Troponin I-based Hypertrophic Cardiomyopathy

BACKGROUND: Transgenic (TG) and gene-targeted models have focused on the mouse. Fundamental differences between the mouse and human exist in Ca(2+) handling during contraction/relaxation and in alterations in Ca(2+) flux during heart failure, with the rabbit more accurately reflecting the human syst...

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Main Authors: Sanbe, Atsushi, James, Jeanne, Tuzcu, Volkan, Nas, Selman, Martin, Lisa, Gulick, James, Osinska, Hanna, Sakthivel, Sadayappan, Klevitsky, Raisa, Ginsburg, Kenneth S., Bers, Donald M., Zinman, Bruce, Lakatta, Edward G., Robbins, Jeffrey
Format: Artigo
Sprog:Inglês
Udgivet: 2005
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1314982/
https://ncbi.nlm.nih.gov/pubmed/15867176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/01.CIR.0000164234.24957.75
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