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Controlled delivery of PDGF-BB for myocardial protection using injectable self-assembling peptide nanofibers

Endothelial cells can protect cardiomyocytes from injury, but the mechanism of this protection is incompletely described. Here we demonstrate that protection of cardiomyocytes by endothelial cells occurs through PDGF-BB signaling. PDGF-BB induced cardiomyocyte Akt phosphorylation in a time- and dose...

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Библиографические подробности
Главные авторы: Hsieh, Patrick C.H., Davis, Michael E., Gannon, Joseph, MacGillivray, Catherine, Lee, Richard T.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2006
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1312017/
https://ncbi.nlm.nih.gov/pubmed/16357943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI25878
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