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Controlled delivery of PDGF-BB for myocardial protection using injectable self-assembling peptide nanofibers

Endothelial cells can protect cardiomyocytes from injury, but the mechanism of this protection is incompletely described. Here we demonstrate that protection of cardiomyocytes by endothelial cells occurs through PDGF-BB signaling. PDGF-BB induced cardiomyocyte Akt phosphorylation in a time- and dose...

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Detalhes bibliográficos
Main Authors: Hsieh, Patrick C.H., Davis, Michael E., Gannon, Joseph, MacGillivray, Catherine, Lee, Richard T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1312017/
https://ncbi.nlm.nih.gov/pubmed/16357943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI25878
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