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Rapid and quantitative detection of homologous and non-homologous recombination events using three oligonucleotide MLPA

Embryonic stem (ES) cell technology allows modification of the mouse germline from large deletions and insertions to single nucleotide substitutions by homologous recombination. Identification of these rare events demands an accurate and fast detection method. Current methods for detection rely on S...

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Main Authors: Langerak, Petra, Nygren, Anders O. H., Schouten, Jan P., Jacobs, Heinz
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1310898/
https://ncbi.nlm.nih.gov/pubmed/16340005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gni187
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