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Coupling DNA-binding and ATP hydrolysis in Escherichia coli RecQ: role of a highly conserved aromatic-rich sequence

RecQ enzymes are broadly conserved Superfamily-2 (SF-2) DNA helicases that play critical roles in DNA metabolism. RecQ proteins use the energy of ATP hydrolysis to drive DNA unwinding; however, the mechanisms by which RecQ links ATPase activity to DNA-binding/unwinding are unknown. In many Superfami...

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Bibliographic Details
Main Authors: Zittel, Morgan C., Keck, James L.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2005
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1310897/
https://ncbi.nlm.nih.gov/pubmed/16340008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki999
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