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Hinge-mediated dimerization of SMC protein is essential for its dynamic interaction with DNA

Structural maintenance of chromosomes (SMC) proteins play central roles in regulating higher order chromosome dynamics from bacteria to humans. As judged by electron microscopy, the SMC homodimer from Bacillus subtilis (BsSMC) is composed of two antiparallel, coiled-coil arms with a flexible hinge....

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Main Authors: Hirano, Michiko, Hirano, Tatsuya
格式: Artigo
語言:Inglês
出版: Oxford University Press 2002
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC131072/
https://ncbi.nlm.nih.gov/pubmed/12411491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf575
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