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Hinge-mediated dimerization of SMC protein is essential for its dynamic interaction with DNA

Structural maintenance of chromosomes (SMC) proteins play central roles in regulating higher order chromosome dynamics from bacteria to humans. As judged by electron microscopy, the SMC homodimer from Bacillus subtilis (BsSMC) is composed of two antiparallel, coiled-coil arms with a flexible hinge....

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Detalhes bibliográficos
Main Authors: Hirano, Michiko, Hirano, Tatsuya
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC131072/
https://ncbi.nlm.nih.gov/pubmed/12411491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf575
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