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Traffic of genetic information between segmental duplications flanking the typical 22q11.2 deletion in velo-cardio-facial syndrome/DiGeorge syndrome

Velo-cardio-facial syndrome/DiGeorge syndrome results from unequal crossing-over events between two 240-kb low-copy repeats termed LCR22 (LCR22-2 and LCR22-4) on Chromosome 22q11.2, comprised of modules, each of which are >99% identical in sequence. To delineate regions in the LCR22s that might c...

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Detalhes bibliográficos
Main Authors: Pavlicek, Adam, House, Reniqua, Gentles, Andrew J., Jurka, Jerzy, Morrow, Bernice E.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1310636/
https://ncbi.nlm.nih.gov/pubmed/16251458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.4281205
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