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Allergen-induced peribronchial fibrosis and mucus production mediated by IκB kinase β-dependent genes in airway epithelium

In response to inflammation or injury, airway epithelial cells express inducible genes that may contribute to allergen-induced airway remodeling. To determine the contribution of epithelial cell NF-κB activation to the remodeling response, we generated CC10-Cre(tg)/Ikkβ(Δ/Δ) mice in which NF-κB sign...

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Detalhes bibliográficos
Main Authors: Broide, David H., Lawrence, Toby, Doherty, Taylor, Cho, Jae Youn, Miller, Marina, McElwain, Kirsti, McElwain, Shauna, Karin, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1308936/
https://ncbi.nlm.nih.gov/pubmed/16317067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509235102
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