In Vitro Activity of Caspofungin (MK-0991) against Candida albicans Clinical Isolates Displaying Different Mechanisms of Azole Resistance

Caspofungin inhibits the synthesis of 1,3-β-d-glucan, a key step in fungal cell wall biosynthesis. Here we report on its potent in vitro activity (MIC at which 90% of the isolates tested are inhibited = 1 μg per ml of RPMI medium) against 32 Candida albicans fluconazole-susceptible and -resistant cl...

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Bibliografiske detaljer

Udgivet i:	J Clin Microbiol
Principais autores:	Bachmann, Stefano P., Patterson, Thomas F., López-Ribot, José L.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2002
Fag:	Mycology
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC130826/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12037093/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JCM.40.6.2228-2230.2002
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