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Tailoring the activity of restriction endonuclease PleI by PNA-induced DNA looping

DNA looping is one of the key factors allowing proteins bound to different DNA sites to signal one another via direct contacts. We demonstrate that DNA looping can be generated in an arbitrary chosen site by sequence-directed targeting of double-stranded DNA with pseudocomplementary peptide-nucleic...

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Bibliographische Detailangaben
Hauptverfasser: Protozanova, Ekaterina, Demidov, Vadim V., Soldatenkov, Viatcheslav, Chasovskikh, Sergey, Frank-Kamenetskii, Maxim D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1307623/
https://ncbi.nlm.nih.gov/pubmed/12231505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvf192
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