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Tailoring the activity of restriction endonuclease PleI by PNA-induced DNA looping

DNA looping is one of the key factors allowing proteins bound to different DNA sites to signal one another via direct contacts. We demonstrate that DNA looping can be generated in an arbitrary chosen site by sequence-directed targeting of double-stranded DNA with pseudocomplementary peptide-nucleic...

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Detalhes bibliográficos
Main Authors: Protozanova, Ekaterina, Demidov, Vadim V., Soldatenkov, Viatcheslav, Chasovskikh, Sergey, Frank-Kamenetskii, Maxim D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1307623/
https://ncbi.nlm.nih.gov/pubmed/12231505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvf192
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