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Protective Immunity to the Larval Stages of Onchocerca volvulus Is Dependent on Toll-Like Receptor 4

Toll-like receptor 4 (TLR4) has been shown to be important for the induction of Th2-dependent immune responses in mice. Protective immunity against larval Onchocerca volvulus in mice depends on the development of a Th2 immune response mediated by both interleukin-4 (IL-4) and IL-5. In addition, O. v...

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Autori principali: Kerepesi, Laura A., Leon, Ofra, Lustigman, Sarah, Abraham, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1307100/
https://ncbi.nlm.nih.gov/pubmed/16299326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.12.8291-8297.2005
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