Decreased In Situ Expression of Interleukin-10 Receptor Is Correlated with the Exacerbated Inflammatory and Cytotoxic Responses Observed in Mucosal Leishmaniasis

Human infection with Leishmania braziliensis can lead to cutaneous leishmaniasis (CL) or mucosal leishmaniasis (ML). We hypothesize that the intense tissue destruction observed in ML is a consequence of an uncontrolled exacerbated inflammatory immune response, with cytotoxic activity. For the first...

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Bibliographic Details
Main Authors: Faria, Daniela R., Gollob, Kenneth J., Barbosa, José, Schriefer, Albert, Machado, Paulo R. L., Lessa, Hélio, Carvalho, Lucas P., Romano-Silva, Marco Aurélio, de Jesus, Amélia R., Carvalho, Edgar M., Dutra, Walderez O.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Fungal and Parasitic Infections
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1307048/
https://ncbi.nlm.nih.gov/pubmed/16299275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.12.7853-7859.2005
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