Decreased In Situ Expression of Interleukin-10 Receptor Is Correlated with the Exacerbated Inflammatory and Cytotoxic Responses Observed in Mucosal Leishmaniasis

Human infection with Leishmania braziliensis can lead to cutaneous leishmaniasis (CL) or mucosal leishmaniasis (ML). We hypothesize that the intense tissue destruction observed in ML is a consequence of an uncontrolled exacerbated inflammatory immune response, with cytotoxic activity. For the first...

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Main Authors: Faria, Daniela R., Gollob, Kenneth J., Barbosa, José, Schriefer, Albert, Machado, Paulo R. L., Lessa, Hélio, Carvalho, Lucas P., Romano-Silva, Marco Aurélio, de Jesus, Amélia R., Carvalho, Edgar M., Dutra, Walderez O.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Fungal and Parasitic Infections
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1307048/
https://ncbi.nlm.nih.gov/pubmed/16299275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.12.7853-7859.2005
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