A Leucine-Rich Motif Targets Pseudomonas aeruginosa ExoS within Mammalian Cells

Type III cytotoxins contribute to the ability of bacterial pathogens to subvert the host innate immune system. ExoS (453 amino acids) is a bifunctional type III cytotoxin produced by Pseudomonas aeruginosa. Residues 96 to 232 comprise a Rho GTPase activating protein domain, while residues 233 to 453...

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Hlavní autoři: Zhang, Yue, Barbieri, Joseph T.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2005
Témata:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1307044/
https://ncbi.nlm.nih.gov/pubmed/16299285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.12.7938-7945.2005
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