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An Early Intestinal Mucosal Source of Gamma Interferon Is Associated with Resistance to and Control of Cryptosporidium parvum Infection in Mice

Resistance to and control of Cryptosporidium parvum infection in mice in the absence of adaptive immunity appears to be gamma interferon (IFN-γ) dependent. Using an IFN-γ-neutralizing antibody in a murine model, we demonstrated increased susceptibility to infection within 24 h. We correlated this ea...

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Autori principali: Leav, Brett A., Yoshida, Masaru, Rogers, Kathleen, Cohen, Seth, Godiwala, Nihal, Blumberg, Richard S., Ward, Honorine
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1307021/
https://ncbi.nlm.nih.gov/pubmed/16299343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.12.8425-8428.2005
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