An Early Intestinal Mucosal Source of Gamma Interferon Is Associated with Resistance to and Control of Cryptosporidium parvum Infection in Mice

Resistance to and control of Cryptosporidium parvum infection in mice in the absence of adaptive immunity appears to be gamma interferon (IFN-γ) dependent. Using an IFN-γ-neutralizing antibody in a murine model, we demonstrated increased susceptibility to infection within 24 h. We correlated this ea...

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Autores principales: Leav, Brett A., Yoshida, Masaru, Rogers, Kathleen, Cohen, Seth, Godiwala, Nihal, Blumberg, Richard S., Ward, Honorine
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2005
Materias:
Fungal and Parasitic Infections
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1307021/
https://ncbi.nlm.nih.gov/pubmed/16299343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.12.8425-8428.2005
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