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Adenoviral gene transfer of endothelial nitric-oxide synthase (eNOS) partially restores normal pulmonary arterial pressure in eNOS-deficient mice

It has been shown that mice deficient in the gene coding for endothelial nitric-oxide synthase (eNOS) have increased pulmonary arterial pressure and pulmonary vascular resistance. In the present study, the effect of transfer to the lung of an adenoviral vector encoding the eNOS gene (AdCMVeNOS) on p...

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Autori principali: Champion, Hunter C., Bivalacqua, Trinity J., Greenberg, Stanley S., Giles, Thomas D., Hyman, Albert L., Kadowitz, Philip J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC130619/
https://ncbi.nlm.nih.gov/pubmed/12237402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.182225899
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