Delayed onset of brain edema and mislocalization of aquaporin-4 in dystrophin-null transgenic mice

Cerebral water accumulation was studied during induction of brain edema in dystrophin-null transgenic mice (mdx-βgeo) and control mice. Immunofluorescence and immunoelectron microscopic analyses of dystrophin-null brains revealed a dramatic reduction of AQP4 (aquaporin-4) in astroglial end-feet surr...

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Main Authors: Vajda, Zsolt, Pedersen, Michael, Füchtbauer, Ernst-Martin, Wertz, Karin, Stødkilde-Jørgensen, Hans, Sulyok, Endre, Dóczi, Tamás, Neely, John D., Agre, Peter, Frøkiær, Jørgen, Nielsen, Søren
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2002
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC130598/
https://ncbi.nlm.nih.gov/pubmed/12232046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.192457099
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