Delayed K(+) clearance associated with aquaporin-4 mislocalization: Phenotypic defects in brains of α-syntrophin-null mice

Recovery from neuronal activation requires rapid clearance of potassium ions (K(+)) and restoration of osmotic equilibrium. The predominant water channel protein in brain, aquaporin-4 (AQP4), is concentrated in the astrocyte end-feet membranes adjacent to blood vessels in neocortex and cerebellum by...

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Hlavní autoři: Amiry-Moghaddam, Mahmood, Williamson, Anne, Palomba, Maria, Eid, Tore, de Lanerolle, Nihal C., Nagelhus, Erlend A., Adams, Marvin E., Froehner, Stanley C., Agre, Peter, Ottersen, Ole P.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2003
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC263862/
https://ncbi.nlm.nih.gov/pubmed/14597704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2336064100
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