Expression of the integrin α(E)β(7) identifies unique subsets of CD25(+) as well as CD25(−) regulatory T cells

Regulatory CD25(+)CD4(+) T cells are considered as important players in T cell homeostasis and self-tolerance. Here we report that the integrin α(E)β(7), which recognizes epithelial cadherin, identifies the most potent subpopulation of regulatory CD25(+) T cells. Strikingly, CD25-negative α(E)(+)CD4...

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Autori principali: Lehmann, Joachim, Huehn, Jochen, de la Rosa, Maurus, Maszyna, Frank, Kretschmer, Ute, Krenn, Veit, Brunner, Monika, Scheffold, Alexander, Hamann, Alf
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2002
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC130581/
https://ncbi.nlm.nih.gov/pubmed/12242333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.192162899
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