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Galectin-1 is a stromal cell ligand of the pre-B cell receptor (BCR) implicated in synapse formation between pre-B and stromal cells and in pre-BCR triggering

Although preB cell-receptor (pre-BCR) formation and cell-surface expression is essential for B cell development, pre-BCR generation of signal transduction remains elusive. Here, we report that recombinant pre-BCRs and the surrogate light chain bind specifically to the bone marrow stromal cell galect...

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Detalhes bibliográficos
Main Authors: Gauthier, Laurent, Rossi, Benjamin, Roux, Florence, Termine, Elise, Schiff, Claudine
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC130578/
https://ncbi.nlm.nih.gov/pubmed/12271131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.202323999
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