טוען...
A dominant-negative MEC3 mutant uncovers new functions for the Rad17 complex and Tel1
The Rad17-Mec3-Ddc1 complex is essential for the cellular response to genotoxic agents and is thought to be important for sensing DNA lesions. Deletion of any of the RAD17, MEC3 or DDC1 genes abolishes the G(1) and G(2) and impairs the intra-S DNA-damage checkpoints. We characterize a dominant-negat...
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| Main Authors: | , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
The National Academy of Sciences
2002
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC130575/ https://ncbi.nlm.nih.gov/pubmed/12271137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.202463999 |
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